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In a recent study by Mishra et al., it has been shown that gut microbiota in obese mice and humans have reduced ability for ethanolamine metabolism that resulted in increased intestinal permeability (Mishra et al., 2023)
Expert Opinion on Therapeutic Targets, 20(10), 12591265
Stronger effects can also lead to more severe side effects and a greater need for monitoring
Semaglutide has not been well-studied in breastfeeding mothers, and small amounts may pass into breast milk
Combination therapies and precision medicine approaches tailored to individual disease mechanisms may offer the best hope for meaningful progress in Alzheimers treatment
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